Lignocaine-prilocaine cream in postherpetic neuralgia.

Methaemoglobinaemia in children treated with prilocaine-lignocaine cream.

refer patients for unpleasant investigations was a factor, as was the patients' age, particularly if they were over 75 or under 40.5 We found that the mean delay from the onset of symptoms to surgical treatment was 19 weeks for left sided carcinomas and 29 weeks for right sided carcinomas. This is an improvement on the 38 and 31 weeks, respectively, of 1979.4 This may be due to increased recogn...

Postherpetic neuralgia.

Double-blind comparison of topical lignocaine-prilocaine cream (EMLA) and lignocaine infiltration for arterial cannulation in adults.

In a double-blind, double-dummy study, the efficacy of topical 5% EMLA cream was compared with that of lignocaine infiltration in alleviating the pain of arterial cannulation. Forty unpremedicated adults were allocated randomly to four groups to receive EMLA cream alone, EMLA and 0.9% saline infiltration, EMLA and 1% lignocaine infiltration or placebo cream and 1% lignocaine infiltration. Follo...

Analgesic and anti-inflammatory effects of lignocaine-prilocaine (EMLA) cream in human burn injury.

Pain relief may be improved by reducing sensitization of nociceptive pathways caused by tissue injury. Such a reduction depends mainly on inhibition of local inflammatory changes and the relation between duration of nociceptive block and nociceptive input. In this study we examined if prolonged topical treatment with local anaesthetics could reduce late hyperalgesia and local inflammation after...

Postherpetic Neuralgia and Trigeminal Neuralgia

Postherpetic neuralgia (PHN) is an unpredictable complication of varicella zoster virus- (VZV-) induced herpes zoster (HZ) which often occurs in elderly and immunocompromised persons and which can induce psychosocial dysfunction and can negatively impact on quality of life. Preventive options for PHN include vaccination of high-risk persons against HZ, early use of antiviral agents, and robust ...